Thyroid function in fetuses with chromosomal abnormalities.

Thyroid function in fetuses with chromosomal abnormalities.

During treatment with inhaled beclomethasone the osteocalcin concentrations decreased, as has been observed in patients taking oral corticosteroids. This might imply that during beclomethasone treatment bone formation is depressed, which could result in osteoporosis in the long run. In our pilot study we investigated healthy subjects who used a high dose of beclomethasone for a short period of ...

[Prevalence of congenital abnormalities identified in fetuses with 13, 18 and 21 chromosomal trisomy].

PURPOSE To describe the prevalence of malformations found in fetuses with trisomy of chromosomes 13, 18 and 21 by identifying the most frequent within each condition. METHODS A retrospective cross-sectional study with the analysis of trisomy cases of chromosomes 13, 18 and 21 diagnosed through fetal karyotype obtained by amniocentesis/cordocentesis, between October 1994 and May 2014, at a Tea...

Detection of chromosomal abnormalities and the 22q11 microdeletion in fetuses with congenital heart defects.

Chromosomal abnormalities and the 22q11 microdeletion are implicated in congenital heart defects (CHDs). This study was designed to detect these abnormalities in fetuses and determine the effect of genetic factors on CHD etiology. Between January 2010 and December 2011, 113 fetuses with CHD treated at the Beijing Obstetrics and Gynecology Hospital were investigated, using chromosome karyotyping...

Abnormalities in thyroid function associated with chronic therapy with methadone.

We studied 145 clinically euthyroid patients on maintenance methadone therapy for narcotic withdrawal, to characterize abnormalities in thyroid-function tests induced by methadone. About a third had increased total thyroxin (T4) and total triiodothyronine (T3) concentrations in serum. The mean concentrations of T3, T4, and thyroxin-binding globulin (TBG) in serum were significantly greater (P l...

Frequency and the Type of Chromosomal Abnormalities in Patients with Primary Amenorrhea in Northeast of Iran